Shared tools · Both communitiesA repository of test samples and reference datasets?
Comparing methods needs common inputs with a known answer. A sample described by its projected thickness and the structure of its scatterers can be simulated at any wavelength; real acquisitions of well-characterised phantoms would complete it.
Shared tools · Both communitiesCan we develop a common library of algorithms?
Retrieval methods are implemented many times, in different languages and with different conventions. A shared open-source library with a common data model would help both communities.
Shared tools · Both communitiesWhich figures of merit and which protocol should we use to compare methods?
Sensitivity, resolution, noise, bias and computation time are reported differently from one paper to the next. A handful of metrics, measured on the same data, would turn shared data and code into a benchmark.
Light & coherence · Both communitiesHow should we measure and report the coherence a MoBI system actually sees?
Spatial and temporal coherence are described with different conventions in X-ray and in optics, and are rarely reported next to the results.
Light & coherence · Both communitiesHow much coherence is enough?
Many forward models assume full coherence, while real beams are only partially coherent. Where does the coherent model stop being valid, and what does a partially coherent model cost?
Light & coherence · Both communitiesCan we do quantitative MoBI with broadband illumination?
Polychromatic X-ray beams and white-light sources both blur the modulation and can bias the retrieved signals. Which corrections transfer from one field to the other?
Light & coherenceHow do we “transfer” the interferometry theory across wavelengths?
Under visible illumination, objects are often pure phase objects; under X-ray illumination there is always some attenuation. Approximations valid in the visible cannot always be made with X-rays.
The modulator · Both communitiesWhat is the best modulation topology?
Gratings, checkerboards, random diffusers and speckle, coded or structured patterns: each is defended on its own terms. A fair comparison needs common criteria.
The modulator · Both communitiesHow do we maximise the information gained per photon?
Absorbing modulators throw photons away; phase modulators and scatterers keep them but are harder to model. Dose for X-ray, light budget for the visible: the same trade-off.
The modulator · Both communitiesHow do we characterise a modulator and describe it to the model?
Real modulators deviate from their design in profile, period and stability. How accurately must we know them, and how do we measure them in practice?
The modulator · Both communitiesCan we agree on a trusted end-to-end simulator?
Simulation is used in both communities, but each validates it against different experiments. A common validation case would show which simulators can be trusted for design.
Retrieval & quantification · Both communitiesPhase integration: how do we stay quantitative?
Integrating phase gradients is sensitive to noise, boundary conditions and low spatial frequencies. Reconstructing a wavefront from slopes is also a classical problem in optics.
Retrieval & quantification · Both communitiesHow do we take noise into account efficiently?
Noise enters the forward model, the retrieval and the regularisation. How do we get useful uncertainty estimates without heavy Monte Carlo runs?
Retrieval & quantification · X-ray firstWhat exactly does dark-field measure, and can it be compared between set-ups?
The signal depends on the set-up (propagation distance, modulation scale, wavelength) as well as on the sample. Which sample-intrinsic quantity can we extract?
Retrieval & quantification · Both communitiesHow do we calibrate, and can we calibrate less?
Modulator, detector response, geometry, wavelength: which of these can be recovered from the data itself, and which need a dedicated measurement?
Pushing the limits · Both communitiesWhat can spectral information add?
Energy-resolved detectors and hyperspectral cameras can separate absorption, phase, scattering and materials. What is gained over a single band, and at what cost?
Pushing the limits · Both communitiesWhat are the real limits of super-resolution with modulation?
Modulation can encode information below the pixel size. What sets the limit, and when is a claimed gain in resolution real?
Pushing the limits · X-ray firstHow do we represent and interpret directional, multi-contrast signals?
Dark-field and scattering can depend on direction and scale. How do we describe them compactly, and how do band-resolved descriptions compare with tensor-like ones?
Pushing the limits · Visible firstBeyond phase and beyond X-rays: which other contrasts and wavelengths are within reach?
Polarisation-sensitive contrast in the visible may have equivalents elsewhere, and EUV, terahertz or neutrons could use the same ideas. What transfers, and what must change?
Pushing the limits · Both communitiesCan we trust learning-based retrieval for quantitative work?
Networks trained on simulations or limited data can look convincing and still be biased. How do we validate them, and what should be reported with the results?
Pushing the limits · X-ray firstHow can we increase the acquisition speed?
A balance between noise, the information we can still extract, and grating optimisation.
Bring the one that keeps you up. Someone here has probably seen it from the other side.